Company Filing History:
Years Active: 2020
Title: John R Cressman: Innovator in Nanoparticle Bioconjugates
Introduction
John R Cressman is a notable inventor based in Fairfax Station, VA (US). He has made significant contributions to the field of bioconjugates, particularly in the development of multifunctional nanoparticles. His work focuses on innovative solutions for detecting cellular membrane potential, which has implications in various scientific and medical applications.
Latest Patents
Cressman holds a patent for "Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential." This invention involves a construct designed to detect cellular membrane potential using a nanoparticle that acts as an electron donor. The construct includes a modular peptide that is attached to the nanoparticle, which comprises a nanoparticle association domain, a motif for mediating peptide insertion into the plasma membrane, and an attachment point for an electron acceptor. The nanoparticle can be a quantum dot, while the electron acceptor can be C60 fullerene. The photoacoustic emission from this construct correlates with the cellular membrane potential, showcasing its potential for advanced cellular studies.
Career Highlights
Cressman is currently associated with the United States Navy, where he contributes his expertise in nanoparticle technology. His work is pivotal in advancing the understanding of cellular functions and developing new methodologies for research in cellular biology.
Collaborations
Throughout his career, Cressman has collaborated with esteemed colleagues, including James B Delehanty and Michael H Stewart. These collaborations have enriched his research and expanded the impact of his innovations in the scientific community.
Conclusion
John R Cressman is a distinguished inventor whose work in multifunctional nanoparticle bioconjugates is paving the way for new advancements in cellular research. His contributions are vital for the ongoing exploration of cellular mechanisms and potential medical applications.