Company Filing History:
Years Active: 2013-2015
Title: Innovations by John Maddison in Medical Imaging
Introduction
John Maddison is a notable inventor based in Sussex, GB, recognized for his contributions to the field of medical imaging. With a total of two patents to his name, Maddison has made significant strides in optimizing the analysis of cell nuclei, which is crucial for histological studies.
Latest Patents
Maddison's latest patents include a method for optimizing the initialization and convergence of active contours for segmentation of cell nuclei in histological sections. This computer-implemented segmentation method processes images representing multiple nuclei, utilizing a set of instructions executed by a computer's processor. The method involves thresholding a grey-scale image to create a black and white image, identifying and extracting objects, and applying an edge detector to improve the segmentation results. Additionally, overlapping nuclei are split to enhance accuracy.
Another significant patent involves a microscopy analysis technique that analyzes cell nuclei using images captured from a bright field microscope. This method retrieves quantitative information regarding different types of chromatin within the cell nuclei, such as heterochromatin and euchromatin. The technique is based on segmented cell nuclei, allowing for the determination of greyscale distribution related to the chromatin types and their structural characteristics.
Career Highlights
Maddison is currently affiliated with the Institute for Medical Informatics, where he continues to develop innovative solutions in medical imaging. His work has been instrumental in advancing the understanding of cellular structures and their implications in medical research.
Collaborations
Maddison collaborates with esteemed colleagues, including Havard E Danielsen and Birgitte Nielsen, who contribute to his research endeavors and enhance the impact of his inventions.
Conclusion
John Maddison's innovative work in medical imaging and cell analysis exemplifies the importance of technological advancements in healthcare. His patents reflect a commitment to improving diagnostic methods and understanding cellular behavior, ultimately benefiting the medical community.