Company Filing History:
Years Active: 2015
Title: Innovations in Immunotherapy: The Contributions of John M Wigginton
Introduction
John M Wigginton is a notable inventor based in Collegeville, NJ (US), recognized for his significant contributions to the field of immunotherapy. His work primarily focuses on developing antibodies that target the PD-L1 signaling pathway, which plays a crucial role in cancer treatment. With a patent portfolio that includes innovative methods for treating cancer, Wigginton's research has the potential to impact many lives.
Latest Patents
Wigginton holds a patent for "Antibodies that bind PD-L1 and uses thereof." This patent outlines a method for immunotherapy aimed at subjects afflicted with cancer. The method involves administering a composition that contains a therapeutically effective amount of an antibody that inhibits signaling from the PD-1/PD-L1 pathway. Additionally, the patent describes a process for selecting suitable candidates for immunotherapy based on the expression levels of PD-L1 in tissue samples. The invention also includes rabbit monoclonal antibodies (mAbs) that specifically bind to PD-L1 antigens in formalin-fixed, paraffin-embedded (FFPE) tissue samples, along with an automated immunohistochemistry (IHC) method for assessing cell surface expression.
Career Highlights
Wigginton is currently associated with Bristol-Myers Squibb Company, a leading biopharmaceutical company known for its innovative therapies. His work at the company has allowed him to collaborate with other talented professionals in the field, further enhancing the development of cancer treatments.
Collaborations
Some of Wigginton's notable coworkers include John P Cogswell and Stacie M Goldberg. Their collaborative efforts contribute to the advancement of research and development in immunotherapy.
Conclusion
John M Wigginton's innovative work in the field of immunotherapy exemplifies the impact of targeted treatments in cancer care. His contributions, particularly in developing antibodies that inhibit the PD-1/PD-L1 signaling pathway, are paving the way for more effective cancer therapies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.