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Years Active: 2015
Title: The Innovations of John C Schmitz, Sr.
Introduction
John C Schmitz, Sr. is a notable inventor based in Pittsburgh, PA. He has made significant contributions to the field of molecular biology, particularly in the development of modified siRNA molecules. His work has implications for enhancing cytotoxicity in therapeutic applications.
Latest Patents
John C Schmitz, Sr. holds a patent for "Modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity." This patent describes a synthesized siRNA molecule where the sense strand has one or more uridine bases replaced by nucleoside analogs, such as 5-fluoro-2'-deoxyuridine (FdU). This innovation represents a step forward in the design of RNA molecules for therapeutic use.
Career Highlights
Throughout his career, Schmitz has worked with esteemed organizations, including the United States Government as represented by the Department of Veterans Affairs and the University of Pittsburgh. His experience in these institutions has allowed him to contribute to important research and development projects.
Collaborations
Some of his notable coworkers include Edward Chu and William H Gmeiner. Their collaborative efforts have likely enriched the research environment and fostered innovative solutions in their respective fields.
Conclusion
John C Schmitz, Sr. is a distinguished inventor whose work in modified siRNA molecules has the potential to impact therapeutic strategies significantly. His contributions to science and collaboration with esteemed institutions highlight his commitment to advancing medical research.