Company Filing History:
Years Active: 2006
Title: John C Castle: Innovator in Acetyl-CoA Carboxylase Research
Introduction
John C Castle is a notable inventor based in Seattle, WA (US). He has made significant contributions to the field of biochemistry, particularly in the study of acetyl-CoA carboxylase 2 (ACC2). His work has implications for understanding metabolic processes and potential therapeutic applications.
Latest Patents
John C Castle holds a patent for an alternatively spliced isoform of acetyl-CoA carboxylase 2 (ACC2). The present invention features nucleic acids and polypeptides encoding novel splice variant isoforms of ACC2. The polynucleotide sequence of ACC2sv1 is provided by SEQ ID NO 3, while the amino acid sequence of ACC2sv1 is provided by SEQ ID NO 4. This invention also includes methods for using ACC2sv1 polynucleotides and proteins to screen for compounds that bind to ACC2sv1.
Career Highlights
Castle is associated with Rosetta Inpharmatics, Inc., where he has been able to apply his expertise in molecular biology and genetics. His work at the company has allowed him to explore innovative approaches to understanding metabolic regulation.
Collaborations
Throughout his career, John C Castle has collaborated with esteemed colleagues such as Zhengyan Kan and Philip W Garrett-Engele. These