Company Filing History:
Years Active: 2018-2024
Title: Jeoffrey Schageman: Innovator in Gene Fusion Detection
Introduction
Jeoffrey Schageman is a notable inventor based in Austin, Texas, recognized for his contributions to the field of molecular biology. He holds four patents that focus on advanced methods for detecting gene fusions, which are critical in understanding various genetic conditions and diseases.
Latest Patents
One of Schageman's latest patents is titled "Methods for partner agnostic gene fusion detection." This innovative method involves amplifying a nucleic acid sample using a primer pool to produce multiple amplicons. The primers target various exon-exon junctions of a driver gene, allowing for the sequencing and alignment of the amplicons to a reference sequence. The process includes normalizing read counts and applying baseline corrections to detect gene fusion events without prior knowledge of specific fusion partners.
Another significant patent is "Methods for detection of fusions using compressed molecular tagged nucleic acid." This method focuses on compressing nucleic acid sequence data associated with molecular tag sequences. It determines consensus sequence reads and alignments for families of sequence reads, generating a compressed data structure that aids in detecting fusions effectively.
Career Highlights
Jeoffrey Schageman is currently employed at Life Technologies Corporation, where he continues to innovate in the field of genetic research. His work has significantly advanced the methodologies used in gene fusion detection, contributing to the broader understanding of genetic anomalies.
Collaborations
Throughout his career, Schageman has collaborated with talented individuals such as Rajesh Gottimukkala and Fiona Hyland. These collaborations have fostered a productive environment for innovation and research in molecular biology.
Conclusion
Jeoffrey Schageman's work in gene fusion detection exemplifies the impact of innovative thinking in the field of molecular biology. His patents not only enhance the understanding of genetic conditions but also pave the way for future advancements in genetic research.