Company Filing History:
Years Active: 2002-2005
Title: Innovations of Jenson Qi in Serine Protease Research
Introduction
Jenson Qi is a notable inventor based in Branchburg, NJ (US), recognized for his contributions to the field of molecular biology and protease research. With a total of 10 patents to his name, he has made significant strides in understanding serine proteases and their potential applications in various medical and industrial fields.
Latest Patents
One of Jenson Qi's latest patents involves the molecular identification of a cDNA encoding a novel serine protease termed protease T. This invention describes the deduced amino acid sequence that encodes a prepro form of 290 amino acids. The alignment of this sequence with other well-characterized serine proteases indicates that it belongs to the S1 serine protease family. The protease T mRNA has been found to be expressed in various tissues, including the stomach, testis, retina, fibroblasts, spinal cord, and several regions of the brain. Additionally, protease T mRNA is present in leukocytes and the Jurkat T cell line, suggesting its involvement in gastric, testicular, retinal, dermatological, neurological/neurodegenerative, and immunological disorders. The protease T gene maps to human chromosome 16p13.3, near the tryptase locus. The enzymatically active protease T generated by Qi is suitable for further biochemical analyses to identify physiological substrates and specific modulators.
Career Highlights
Jenson Qi is currently associated with Ortho-McNeil Pharmaceutical Corporation, where he continues to advance his research in protease technology. His work has garnered attention for its potential implications in therapeutic applications and cleaning compositions that utilize human serine protease T.
Collaborations
Jenson Qi has collaborated with notable colleagues, including Andrew Lawrence Darrow and Patricia Andrade-Grodon, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Jenson Qi's innovative work in the field of serine proteases exemplifies the intersection of molecular biology and practical applications. His patents and ongoing research hold promise for advancements in medical and industrial fields, showcasing the importance of innovation in science.