Company Filing History:
Years Active: 2024
Title: The Innovations of Jen-Shyang Ni
Introduction
Jen-Shyang Ni is a prominent inventor based in Shenzhen, China. He is known for his significant contributions to the field of materials science, particularly in the development of novel compounds for imaging applications. His work has led to advancements in the use of near-infrared (NIR) fluorescent dyes, which have important implications for medical diagnostics and therapeutic procedures.
Latest Patents
Jen-Shyang Ni holds a patent for "NIR-II emissive luminogens." This patent describes small molecule compounds that exhibit aggregation-induced emission (AIE) characteristics. These compounds feature donor-acceptor (D-A) structural NIR fluorophores based on 1,3-bis(dicyanomethylene)indan (BDCI), which serves as a strong and steric electron-deficient acceptor. A twisted quasi-double bond (TQDB) connects each electron donor with the acceptor. The compounds are designed for use as NIR-II fluorescent dyes in in vivo imaging. They can conjugate with bioactive molecules, such as peptides, sugars, aptamers, and antibodies, to create specific and active NIR-II fluorescent probes. These compounds have potential applications in cancer cell-targeted imaging, accurate disease diagnosis, and image-guided phototherapy. He has 1 patent to his name.
Career Highlights
Throughout his career, Jen-Shyang Ni has worked with esteemed institutions, including The Hong Kong University of Science and Technology and the HKUST Shenzhen Research Institute. His research has garnered attention for its innovative approach to solving complex problems in imaging technology.
Collaborations
Jen-Shyang Ni has collaborated with notable researchers in his field, including Benzhong Tang and Pengfei Zhang. Their joint efforts have contributed to the advancement of NIR fluorescent probes and their applications in medical science.
Conclusion
Jen-Shyang Ni's work in developing NIR-II emissive luminogens represents a significant advancement in imaging technology. His contributions have the potential to enhance medical diagnostics and treatment methodologies.