Company Filing History:
Years Active: 1998
Title: Inventor Profile - Jeffrey S. Mogil
Introduction
Jeffrey S. Mogil, based in Vancouver, WA, is an innovative researcher with a focus on developing novel therapeutic solutions targeted at the opioid crisis. He has been instrumental in creating new anti-opioid receptor proteins and their applications, significantly contributing to the field of pain management.
Latest Patents
Mogil holds a patent relating to "Opioid antagonists and methods of their use." This invention outlines a groundbreaking approach involving a mammalian anti-opioid receptor protein known as OFQR, along with peptide ligands such as OFQ. The patent describes the methods of using the OFQ peptide and its analogues to reverse the physiologic effects of opiates like morphine. Central to this invention is the heptadecapeptide structure of the OFQ peptide with an FGGF aminoterminal motif that selectively binds to the OFQR. This innovative work aims to provide alternatives for patients by antagonizing opioid-mediated effects without increasing nociceptive sensitivity.
Career Highlights
Mogil's career is marked by significant contributions to medical research and pharmacology. His efforts aim to enhance the understanding and treatment of pain, especially in contexts where traditional opioids may pose risks of dependency and adverse side effects.
Collaborations
Throughout his career, Mogil has collaborated with esteemed colleagues, including David K. Grandy and Judith E. Grisel. These collaborations have fostered an environment of interdisciplinary research, leading to significant advancements in opioid receptor research and the development of therapeutic agents.
Conclusion
Jeffrey S. Mogil represents a vital presence in the realm of innovation in pain management. His patent on opioid antagonists showcases his commitment to improving health outcomes and addressing the public health challenges posed by opiate use. Through his career and collaborations, Mogil continues to contribute to advancements in medical science, paving the way for safer alternatives in pain relief therapies.