Jeffrey C Edman

Title: **Innovative Insights into Jeffrey C Edman and His Patents**

Introduction

Jeffrey C Edman is a notable inventor based in Mill Valley, California, recognized for his contributions to the field of biotechnology. With one patent to his name, Edman has made significant advancements in understanding receptor tyrosine kinases, which play crucial roles in cellular signaling and cancer biology.

Latest Patents

Edman's most prominent patent is focused on the "Receptor tyrosine kinase with a discoidin-type binding domain." This invention describes a breast carcinoma tyrosine phosphoprotein known as DDR (Discoidin Domain Receptor). The DDR cDNA reveals a polypeptide featuring a C-terminal tyrosine kinase domain and an N-terminal domain analogous to the lectin discoidin I. Notably, these domains are linked by a distinctive hydrophilic proline/glycine-rich region that contains a transmembrane sequence. The unique architecture of the proline/glycine-rich area indicates a special geometry of interaction with ligands or substrates, suggesting potential interactions between discoidin I-type domains and specific cell surface molecules.

Career Highlights

Throughout his career, Jeffrey C Edman has focused on innovative research in cellular signaling mechanisms and their implications in cancer. His patent reflects his expertise in biotechnology and his commitment to advancing scientific knowledge in this domain.

Collaborations

In his research endeavors, Edman has collaborated with distinguished colleagues, including Jeffrey D Johnson and William J Rutter. These partnerships have likely contributed to the depth and breadth of his work, allowing for a richer exploration of the complexities involved in receptor tyrosine kinases.

Conclusion

Jeffrey C Edman's work exemplifies significant innovation within the realm of biochemical research. Through his patent and collaborations, he has contributed valuable insights that may pave the way for new therapeutic approaches in treating breast carcinoma and other related conditions. The impact of his research on receptor tyrosine kinases emphasizes the importance of continued exploration in the field of biotechnology and cancer research.