Company Filing History:
Years Active: 2022
Title: Jeff Gole: Innovator in Nucleic Acid Research
Introduction
Jeff Gole is a prominent inventor based in Cambridge, MA (US). He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid research. His innovative work has led to the development of methods that enhance the analysis of target genes by minimizing interference from unwanted genetic segments.
Latest Patents
Jeff Gole holds a patent for "Methods for selectively suppressing non-target sequences." This invention relates to the negative selection of nucleic acids. It provides methods and systems that effectively remove unwanted segments of nucleic acid in a sample. This allows for the analysis of a target gene or region of interest without interference from these unwanted segments. The process involves obtaining a sample that includes single-stranded nucleic acid with one or more unwanted segments. Complementary nucleic acid is then added to create a double-stranded region that includes the unwanted segment. The double-stranded region is subsequently digested, leaving single-stranded nucleic acid that contains the target gene or region of interest. This method is particularly useful for removing paralogs, pseudogenes, repetitive elements, and other similar segments from the genome.
Career Highlights
Jeff Gole is currently associated with Molecular Loop Biosciences, Inc., where he continues to advance his research and innovations. His work has garnered attention for its potential applications in genetic analysis and biotechnology.
Collaborations
Some of his notable coworkers include Athurva Gore and Mark Umbarger. Their collaborative efforts contribute to the innovative environment at Molecular Loop Biosciences, Inc.
Conclusion
Jeff Gole's contributions to nucleic acid research exemplify the impact of innovative thinking in biotechnology. His patented methods for selectively suppressing non-target sequences represent a significant advancement in the field, enabling more precise genetic analysis.