Company Filing History:
Years Active: 2015-2019
Title: Jeannette Adu-Bobie: Innovator in Immunogenic Bacterial Vesicles
Introduction
Jeannette Adu-Bobie is a prominent inventor based in Siena, Italy. She has made significant contributions to the field of immunology, particularly in the development of innovative bacterial vesicles. With a total of three patents to her name, her work has the potential to advance vaccine technology and improve public health outcomes.
Latest Patents
Adu-Bobie's latest patents focus on immunogenic bacterial vesicles that contain outer membrane proteins. One of her notable inventions involves the knockout of the meningococcal mltA homolog, which results in bacteria that spontaneously release vesicles rich in immunogenic outer membrane proteins. These vesicles can elicit cross-protective antibody responses with higher bactericidal titers than traditional outer membrane vesicles (OMVs) produced through standard methods. The invention provides a bacterium with a knockout mutation of its mltA gene, characterized by a cell wall that includes peptidoglycan and the absence of a protein with lytic transglycosylase activity. Additionally, the invention includes compositions comprising vesicles released into the culture medium during the growth of these bacteria.
Career Highlights
Throughout her career, Jeannette Adu-Bobie has worked with leading companies in the pharmaceutical and biotechnology sectors. Notable organizations include GlaxoSmithKline Biologicals and Novartis Vaccines and Diagnostics. Her experience in these companies has allowed her to contribute to the development of innovative solutions in vaccine research and development.
Collaborations
Adu-Bobie has collaborated with several professionals in her field, including Mariagrazia Pizza and Nathalie Norais. These collaborations have further enriched her research and contributed to her success as an inventor.
Conclusion
Jeannette Adu-Bobie is a trailblazer in the field of immunogenic bacterial vesicles, with her innovative patents paving the way for advancements in vaccine technology. Her work exemplifies the impact of dedicated research and collaboration in the pursuit of public health improvements.