Jean-Philippe Estradier

Title: Jean-Philippe Estradier: Innovator in Peptide Modifications

Introduction

Jean-Philippe Estradier is a notable inventor based in Montreal, Canada. He has made significant contributions to the field of biochemistry, particularly in the development of modified peptides. His work focuses on enhancing the biological activity and stability of peptide compounds.

Latest Patents

Jean-Philippe Estradier holds a patent for "Modified corticotropin releasing factor peptides and uses thereof." This invention relates to compounds that include modified corticotrophin releasing factor peptides, specifically urocortin and its related peptides. The patent details methods for covalently attaching these modified peptides to serum proteins or peptides, resulting in conjugates that exhibit a longer in vivo circulating half-life. These conjugates not only retain some biological activity but also show increased efficacy compared to their unconjugated counterparts. The invention provides methods for treating and preventing various diseases through the administration of these innovative compounds.

Career Highlights

Jean-Philippe Estradier is associated with Conjuchem, Inc., where he continues to advance his research in peptide modifications. His work has the potential to impact therapeutic approaches in various medical fields.

Collaborations

He has collaborated with notable colleagues such as Thomas R. Ulich and Karen Thibaudeau, contributing to a dynamic research environment that fosters innovation.

Conclusion

Jean-Philippe Estradier's contributions to peptide research exemplify the importance of innovation in the field of biochemistry. His patented work on modified corticotropin releasing factor peptides showcases the potential for enhanced therapeutic applications.