Jean-Francois Depoisier

Title: Innovations by Jean-Francois Depoisier

Introduction

Jean-Francois Depoisier is a notable inventor based in Mont Saxonnet, France. He has made significant contributions to the field of antibody purification, showcasing his expertise through innovative methods that enhance the efficiency of isolating desired antibody products.

Latest Patents

One of his key patents is titled "Methods of purifying antibodies." This invention provides methods for purifying antibodies using various antibody-specific purification media. It allows for the rapid and efficient separation of mixtures of antibodies, antibody fragments, and/or antibody components. The goal is to isolate a desired antibody product from the mixture. The invention particularly focuses on the purification of bispecific monoclonal antibodies, which possess different specificities for each binding site of the immunoglobulin molecule. This includes antibodies composed of a single heavy chain and two different light chains, one containing a Kappa constant domain and the other a Lambda constant domain. The methods also efficiently purify intact antibodies by separating them from non-intact antibodies, including free light chains.

Career Highlights

Jean-Francois Depoisier is associated with Novimmune SA, a company that specializes in the development of therapeutic antibodies. His work at Novimmune has been instrumental in advancing the field of antibody purification.

Collaborations

He has collaborated with notable colleagues such as Greg Elson and Nicolas Fouque, contributing to the innovative environment at Novimmune.

Conclusion

Jean-Francois Depoisier's contributions to antibody purification represent a significant advancement in the field of biotechnology. His innovative methods and collaborations continue to influence the development of therapeutic antibodies.