Location History:
- Malden, MA (US) (2001 - 2004)
- Lelekovice, CZ (2004)
Company Filing History:
Years Active: 2001-2004
Title: Innovations of Jan Preisler in Mass Spectrometry
Introduction
Jan Preisler is an accomplished inventor based in Lelekovice, Czech Republic. He has made significant contributions to the field of mass spectrometry, particularly in the area of matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy. With a total of three patents to his name, Preisler's work has advanced the capabilities and efficiency of mass spectrometry techniques.
Latest Patents
One of Jan Preisler's latest patents focuses on the on-line and off-line deposition of liquid samples for MALDI-TOF mass spectroscopy. This universal interface allows for continuous on-line liquid sample introduction directly to the time-of-flight mass spectrometer, enhancing throughput and utility. The method involves infusing a solution of sample containing peptides and a matrix into the source chamber of a mass spectrometer at subatmospheric pressure. The sample is then deposited on a moving sample holder, such as a rotating quartz wheel, and desorbed using a nitrogen laser. This innovative approach is particularly beneficial for high-throughput mass spectrometry analysis, as it enables multiplexing and the parallel deposition of multiple samples. Additionally, Preisler has developed an off-line deposition chamber and a method for preparing samples that ensures homogeneous deposition with improved reproducibility.
Career Highlights
Jan Preisler is affiliated with Northeastern University, where he continues to contribute to research and development in mass spectrometry. His work has garnered attention for its practical applications in various scientific fields, enhancing the capabilities of existing commercial mass spectrometers.
Collaborations
Jan Preisler has collaborated with notable colleagues, including Barry L. Karger and Frantisek Foret. These partnerships have further enriched his research and innovation in mass spectrometry.
Conclusion
Jan Preisler's contributions to mass spectrometry through his innovative patents and collaborations have significantly advanced the field. His work continues to influence the efficiency and effectiveness of mass spectrometry techniques, paving the way for future developments.