Company Filing History:
1 out of 5 
1 out of 5,307 
Years Active: 2006
Title: Jan Matthijs Van De Rijn: Innovator in Cancer Diagnosis and Treatment
Introduction
Jan Matthijs Van De Rijn is a notable inventor based in La Honda, California. He has made significant contributions to the field of cancer research, particularly in the diagnosis and management of breast cancer. His innovative work has the potential to improve patient outcomes and advance the understanding of tumor biology.
Latest Patents
Van De Rijn holds a patent for "Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors." This invention provides a variety of reagents for use in the diagnosis and management of breast cancer. It utilizes cDNA microarray technology to identify genes whose expression profile across a large group of tumor samples correlates with that of cytokeratin 5 and cytokeratin 17, which are markers for basal cells of the normal mammary lactation gland. The invention demonstrates that tumors expressing cytokeratin 5/6 and/or 17 have a poor prognosis relative to tumors overall. It provides basal marker genes and their expression products, which can be used for the diagnosis of breast cancer and for identifying therapies for the disease. Notably, the invention includes basal marker genes such as cadherin 3, matrix metalloproteinase 14, and cadherin EGF LAG seven-pass G-type receptor 2. Additionally, it provides antibodies to the polypeptides expressed by these genes and methods of use thereof.
Career Highlights
Throughout his career, Van De Rijn has worked with esteemed organizations, including Applied Genomics, Inc. and Leland Stanford Junior University. His work has been instrumental in advancing cancer research and improving diagnostic techniques.
Collaborations
He has collaborated with prominent scientists in the field, including David Botstein and Patrick O Brown. These collaborations have further enriched his research and contributed to the development of innovative solutions in cancer diagnosis.
Conclusion
Jan Matthijs Van De Rijn is a pioneering inventor whose work in cancer diagnosis and treatment has the potential to significantly impact patient care. His contributions to the field exemplify the importance of innovation in medical research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.