James Malcolm Maclean

Title: Innovations of James Malcolm Maclean

Introduction

James Malcolm Maclean is a notable inventor based in Cape Town, South Africa. He has made significant contributions to the field of biotechnology, particularly in the expression of proteins in plants. With a total of 2 patents, his work has implications for vaccine development and agricultural biotechnology.

Latest Patents

Maclean's latest patents focus on methods for producing influenza virus H5 polypeptides and HPV polypeptides in plants. The first patent describes a method that involves cloning an influenza H5 gene into a vector designed to target plant components. This process includes infiltrating the plant with the vector to transiently express the influenza virus H5 polypeptide and potentially create a transgenic plant. The invention also covers the recovery of the expressed polypeptide and the use of vectors and transgenic plants resulting from this method. The second patent similarly outlines a method for producing HPV polypeptides and influenza virus H5 polypeptides, emphasizing the cloning of relevant genes and the transformation of plant tissue to achieve expression.

Career Highlights

James Malcolm Maclean is affiliated with the University of Cape Town, where he conducts his research and development activities. His work has positioned him as a key figure in the intersection of plant biotechnology and virology.

Collaborations

Maclean collaborates with esteemed colleagues such as Anna-Lise Williamson and Edward Peter Rybicki, contributing to a rich environment of innovation and research.

Conclusion

James Malcolm Maclean's contributions to the field of biotechnology through his patents and collaborations highlight the potential of plant-based systems in producing important viral proteins. His work continues to pave the way for advancements in vaccine development and agricultural applications.