Company Filing History:
Years Active: 2015
Title: Innovations of James John Ludtke
Introduction
James John Ludtke is a notable inventor based in Madison, Wisconsin. He has made significant contributions to the field of biotechnology, particularly in the development of peptide display systems. His work has implications for liver-targeting peptides, which can be crucial for therapeutic applications.
Latest Patents
Ludtke holds a patent for a T7 phage peptide display system and its uses. This invention involves a bacteriophage T7 display vector designed for expressing and displaying an exogenous peptide. The display vector includes a polynucleotide encoding a bacteriophage T7 tail fiber protein p17, with an inactivated hepatocyte-targeting determinant sequence. Additionally, it contains a cloning site within the coding sequence for the tail fiber protein p17 or the capsid protein p10B. The invention also encompasses a host cell containing the display vector, a bacteriophage T7 particle with an exogenous peptide displayed, and a viral lysate containing the assembled bacteriophage T7 particle. Furthermore, it provides a method for determining if a candidate peptide is a liver-targeting peptide or for screening liver-targeting peptides.
Career Highlights
Ludtke is associated with the Wisconsin Alumni Research Foundation, where he continues to innovate and contribute to research in biotechnology. His work has garnered attention for its potential applications in medical science and therapeutic development.
Collaborations
Ludtke has collaborated with notable colleagues, including Alexander V. Sokoloff and Jon Asher Wolff. These collaborations have likely enriched his research and expanded the impact of his inventions.
Conclusion
James John Ludtke's contributions to the field of biotechnology, particularly through his patented T7 phage peptide display system, highlight his innovative spirit and dedication to advancing medical science. His work continues to pave the way for future developments in liver-targeting therapies.