Company Filing History:
Years Active: 2004-2011
Title: Innovations of James Howard Kaysen
Introduction
James Howard Kaysen is a notable inventor based in New Orleans, LA (US). He has made significant contributions to the field of functional proteins, particularly through his innovative methods involving renal cells. With a total of 4 patents, Kaysen's work has the potential to impact medical treatments and therapies.
Latest Patents
Kaysen's latest patents focus on the production of functional proteins, specifically hormones, using renal cells in a three-dimensional culturing process. His method utilizes a rotating wall vessel that responds to shear stress and gravity. This innovative approach allows for the expression of the enzyme 1-α-hydroxylase, which is crucial for generating the active form of vitamin D: 1,25-diOH vitamin D. Additionally, his work includes the co-culture of renal cortical cells that express the gene for erythropoietin, enabling the secretion of this important protein into the culture supernatant. Kaysen's patents also address the modulation of other shear stress response genes, such as toxin receptors megalin and cubulin (gp280). Furthermore, he has developed methods for treating individuals in need with the functional proteins produced through this advanced co-culture process.
Career Highlights
Kaysen's career is marked by his association with the United States of America as represented by the Administrator of NASA. His work has garnered attention for its innovative approach to protein production and its potential applications in healthcare.
Collaborations
Kaysen has collaborated with notable colleagues, including Thomas John Goodwin and Timothy Grant Hammond. Their combined expertise has contributed to the advancement of research in the field of functional proteins.
Conclusion
James Howard Kaysen's contributions to the field of functional proteins through his innovative patents highlight his role as a significant inventor. His work not only advances scientific understanding but also holds promise for future medical applications.