Houston, TX, United States of America

James H Kelly


Average Co-Inventor Count = 1.5

ph-index = 2

Forward Citations = 292(Granted Patents)


Company Filing History:


Years Active: 1994

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2 patents (USPTO):Explore Patents

Title: Innovations by James H. Kelly

Introduction

James H. Kelly is a notable inventor based in Houston, TX, who has made significant contributions to the field of medical technology. He holds two patents that focus on organ support systems and liver assist devices. His work is aimed at improving patient care and addressing critical health issues.

Latest Patents

One of his latest patents is an organ support system designed to modify blood from a patient. This system includes a control system, a venous line coupled to an output of a patient, an arterial line coupled to an input of the patient, and a cell line inserted into a hollow fiber cartridge to form an organ assist device. Blood is passed through this organ assist device, and a small flow is extracted from the extracapillary space to check the integrity of the device. This closed-loop arrangement allows for proper fluid balance without requiring any dialysate, while also detecting and preventing leaks from the cell line to the patient.

Another significant patent is related to a permanent human hepatocyte cell line and its use in liver assist devices. These permanent cell lines exhibit liver-specific biological activity effective for supporting subjects suffering from hepatic failure or insufficiency. The cells are useful in treating various liver disorders, with an example being the HepG2/C3A cell line deposited under ATCC No. CRL-10741. Methods for utilizing these cells in liver assist devices are also provided.

Career Highlights

James H. Kelly has worked with notable organizations such as Hepatix, Inc. and Baylor College of Medicine. His experience in these institutions has contributed to his expertise in developing innovative medical solutions.

Collaborations

Throughout his career, he has collaborated with professionals like Norman L. Sussman and Donn D. Lobdell, enhancing the impact of his inventions through teamwork and shared knowledge.

Conclusion

James H. Kelly's contributions to medical technology through his patents reflect his commitment to improving patient outcomes. His innovative approaches to organ support and liver assist devices are paving the way for advancements in healthcare.

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