Company Filing History:
Years Active: 2002-2006
Title: The Innovative Contributions of James E. Krause
Introduction
James E. Krause is a prominent inventor based in Madison, CT, who has made significant contributions to the field of molecular biology. With a total of 8 patents to his name, Krause's work has focused on melanin concentrating hormone receptors, which play a critical role in both human and animal health.
Latest Patents
Among his most recent patents are two groundbreaking innovations related to monkey and canine melanin concentrating hormone receptors. The first patent provides isolated polynucleotides encoding monkey and canine Melanin Concentrating Hormone (MCH) Type 2 receptors. This innovation includes the development of chimeric polypeptides, vectors, and cells for recombinant expression of these MCH receptor polypeptides. The polynucleotides and polypeptides can be utilized to identify agents that specifically interact with MCH receptors, offering potential therapies for various conditions linked to MCH receptor activation.
The second patent addresses isolated polynucleotides encoding monkey Melanin Concentrating Hormone (MCH) Type 1 receptors. This patent also presents chimeric polypeptides, vectors, and cells for recombinant expression. Similar to the first, the MCH1R polynucleotides and polypeptides can be instrumental in discovering compounds that target MCH receptors, paving the way for therapeutic advancements for both humans and animals dealing with conditions associated with MCH receptor activation.
Career Highlights
Krause's innovative spirit and dedication to research have been instrumental in the success of Neurogen Corporation, where he currently works. His expertise in molecular biology and receptor pharmacology has contributed to the advancement of medical therapies and the understanding of MCH interactions.
Collaborations
Throughout his career, James E. Krause has collaborated with notable colleagues, including Robbin M. Brodbeck and Andrew Y. Thurkauf. These partnerships underscore the collaborative nature of scientific research and the importance of teamwork in driving innovation.
Conclusion
James E. Krause's contributions to the field of molecular biology through his patents reflect his commitment to advancing medical science. His work on melanin concentrating hormone receptors not only enhances our understanding of these critical biological components but also opens new avenues for therapeutic interventions. As an inventor, Krause exemplifies the impact that innovative thinking can have on health and wellness in both humans and animals.