Jack M Widholm

Title: Jack M Widholm: Innovator in Plant Transformation Technologies

Introduction

Jack M Widholm is a notable inventor based in Tolono, Illinois, who has made significant contributions to the field of plant transformation. With a total of five patents to his name, Widholm's work focuses on enhancing plant cell transformation processes, particularly through the use of specific amino acid analogs.

Latest Patents

Widholm's latest patents include innovative methods and compositions that utilize tryptophan analogs, indole analogs, and mixtures thereof as selection agents for transformed plant cells. One of his key patents describes the use of these agents in conjunction with the anthranilate synthase (ASA2) gene, which encodes a feedback-insensitive form of anthranilate synthase. This technology allows for the selection of plant cells that are more resistant to tryptophan analogs and can produce increased levels of tryptophan. Additionally, the patents disclose nucleotide sequences encoding anthranilate synthase genes, including the 5-methyltryptophan resistant Nicotiana anthranilate synthase genes, which are crucial for transforming plant cells and producing resilient plant progenies.

Career Highlights

Throughout his career, Jack M Widholm has worked with esteemed organizations such as the University of Illinois and Lubrizol Genetics, Inc. His research has significantly advanced the understanding and application of plant transformation technologies, making him a respected figure in the field.

Collaborations

Widholm has collaborated with notable colleagues, including Hee-Sook Song and Jeffrey E Brotherton, contributing to the development of innovative solutions in plant biotechnology.

Conclusion

Jack M Widholm's contributions to plant transformation technologies through his patents and collaborations have paved the way for advancements in agricultural biotechnology. His work continues to influence the field and enhance the capabilities of plant cell transformation.