Location History:
- Potomac, MD (US) (1995 - 1999)
- Kula, HI (US) (2002)
- Pukalani, HI (US) (2001 - 2007)
- Bethesda, MD (US) (1999 - 2008)
Company Filing History:
5 out of 3,539 
3 out of 1,217 
1 out of 2,202 
Years Active: 1995-2008
Title: The Innovative Contributions of Jacalyn H. Pierce
Introduction
Jacalyn H. Pierce, an accomplished inventor based in Pukalani, Hawaii, has made significant contributions to the field of biotechnology. With a remarkable portfolio of nine patents, she has dedicated her research efforts to advancing our understanding of platelet-derived growth factors and their receptors.
Latest Patents
Jacalyn's latest patents include groundbreaking work on the compositions of alpha platelet-derived growth factor receptor nucleic acid and protein, outlining a DNA sequence that encodes a novel human type α platelet-derived growth factor receptor protein. This receptor preferentially binds to both the AA homodimer and AB heterodimer forms of platelet-derived growth factor, demonstrating high affinity for the BB homodimer as well. Furthermore, her patents detail methods for identifying alpha PDGFR agonists and antagonists, showcasing how recombinant DNA technology can yield previously unknown types of human PDGF receptor proteins. These innovations enable various applications, including biochemical studies and the production of antibodies, significantly impacting the research landscape in this field.
Career Highlights
Throughout her career, Jacalyn has worked with notable organizations, including the United States Department of Health and the United States Department of Health and Human Services. Her work within these institutions has propelled advancements in health science, particularly in the area of growth factor research.
Collaborations
Jacalyn's research journey includes collaborations with esteemed colleagues such as Stuart A. Aaronson and Toshimitsu Matsui. These partnerships have enhanced the scope of her work and contributed to the successful realization of her inventions.
Conclusion
Jacalyn H. Pierce stands out as a pioneering inventor whose research continues to shape the future of biotechnology. Her patents not only highlight her innovative spirit but also demonstrate the potential for scientific breakthroughs in understanding and utilizing platelet-derived growth factors. As her work progresses, it promises to have lasting impacts on health and medical research.