J Penn Whitley

Title: J Penn Whitley: Innovator in RNA Amplification Technologies

Introduction

J Penn Whitley is a notable inventor based in Austin, TX (US). He has made significant contributions to the field of molecular biology, particularly in the area of RNA amplification. His innovative work has implications for various applications, including gene expression analysis in bacteria.

Latest Patents

Whitley holds a patent for "Methods and compositions for tailing and amplifying RNA." This invention provides methods and compositions that enable tagging and amplification of targeted RNA molecules. The targeted RNA molecules can include non-polyadenylated RNA types such as miRNA, siRNA, rRNA, tRNA, synthetic RNA, or non-polyadenylated mRNA from bacteria. The methods developed by Whitley allow for genome-wide expression analysis of bacterial genes, even in cases where bacterial numbers are too low to purify adequate amounts of RNA for DNA microarray analysis. This innovation is particularly useful for studying bacterial gene expression during host-cell infection. Additionally, the invention includes kits for tagging and amplifying targeted RNA molecules.

Career Highlights

Throughout his career, J Penn Whitley has worked with prominent companies in the biotechnology sector. He has been associated with Applera Corporation and Life Technologies Corporation, where he contributed to advancements in molecular biology technologies.

Collaborations

Whitley has collaborated with various professionals in his field, including George L Murphy, enhancing the impact of his research and innovations.

Conclusion

J Penn Whitley's contributions to RNA amplification technologies have paved the way for significant advancements in molecular biology. His innovative methods and compositions continue to influence research in gene expression analysis.