Jerusalem, Israel

Israel Vlodavsky


Average Co-Inventor Count = 4.3

ph-index = 3

Forward Citations = 92(Granted Patents)


Company Filing History:


Years Active: 1989-1999

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3 patents (USPTO):Explore Patents

Title: Israel Vlodavsky: Innovator in Glycosaminoglycan Research

Introduction

Israel Vlodavsky is a prominent inventor based in Jerusalem, Israel. He has made significant contributions to the field of glycosaminoglycan research, particularly in relation to wound healing processes. With a total of 3 patents, his work has implications for both medical treatments and understanding cellular interactions.

Latest Patents

Vlodavsky's latest patents focus on the attenuation of wound healing processes through the use of glycosaminoglycans. His research highlights the role of heparinases 1, 2, and 3, as well as chondroitinases AC and B, derived from the Gram-negative bacteria Flavobacterium heparinum. These enzymes can be utilized separately or in combination to manipulate cell proliferation. One of his key inventions involves administering heparinases to degrade heparan sulfate components of the extracellular matrix, facilitating the migration of heparin-binding growth factors to adjacent cells. Additionally, he explores how the enzymatic removal of chondroitin sulfates from cell surfaces can enhance the availability of growth factor receptors, thereby influencing cell behavior. Another significant patent addresses the inhibition of heparanase activity, which can be achieved through the administration of heparin or its chemically modified derivatives. This innovation has potential applications in preventing allograft rejection and treating autoimmune diseases such as arthritis.

Career Highlights

Throughout his career, Vlodavsky has worked with notable organizations, including Yeda Research and Development Co. Ltd. and Ibex Technologies R and D, Inc. His research has garnered attention for its innovative approach to understanding and manipulating cellular processes.

Collaborations

Vlodavsky has collaborated with esteemed colleagues, including Amiram Eldor and Yaakov Naparstek. These partnerships have contributed to the advancement of his research and the development of his patents.

Conclusion

Israel Vlodavsky's contributions to glycosaminoglycan research and his innovative patents have the potential to significantly impact medical treatments and our understanding of cellular dynamics. His work exemplifies the importance of innovation in addressing complex biological challenges.

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