Company Filing History:
Years Active: 1993
Title: Innovations of Isaac Edery
Introduction
Isaac Edery is a notable inventor based in Chomedey, Canada. He has made significant contributions to the field of molecular biology, particularly in the area of mRNA research. His innovative work has led to the development of a unique protein that plays a crucial role in the isolation of capped mRNA.
Latest Patents
Isaac Edery holds a patent for a bifunctional protein designed for the isolation of capped mRNA. This protein comprises at least a first functional site that binds to the cap structure of mRNA and a second functional site that binds to a solid support matrix. This design allows the first functional site to remain functionally accessible while being immobilized. The patent also includes a method for generating a cDNA library that predominantly contains full-length cDNAs. This method involves incubating a mixture of mRNA:cDNA hybrids with a single-strand RNA-specific nuclease and the bifunctional protein. The resulting mixture is passed through a column with a support matrix that selectively binds complete mRNA:cDNA hybrids. The full-length cDNA strands are then separated and recovered through competitive elution with a cap analog. Additionally, the patent outlines a method for purifying capped mRNA using the same bifunctional protein.
Career Highlights
Isaac Edery is affiliated with McGill University, where he continues to advance his research in molecular biology. His work has garnered attention for its potential applications in genetic research and therapeutic development.
Collaborations
Isaac has collaborated with esteemed colleagues such as Nahum Sonenberg and Michael Altmann, contributing to the advancement of knowledge in their shared field of expertise.
Conclusion
Isaac Edery's innovative contributions to the field of molecular biology, particularly through his patented bifunctional protein, highlight his role as a significant inventor. His work not only enhances our understanding of mRNA but also paves the way for future advancements in genetic research.