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Years Active: 2015-2019
Title: Innovations and Contributions of Iris Lai King Wong
Introduction
Iris Lai King Wong is a prominent inventor based in Hong Kong, CN. She has made significant contributions to the field of medicinal chemistry, particularly in the development of novel compounds for treating drug resistance in cancers and parasitic infections. With a total of 5 patents, her work showcases her dedication to advancing medical science.
Latest Patents
One of her latest patents focuses on "Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers." This innovative work involves constructing a triazole bridged flavonoid dimer compound library through cycloaddition reactions. The compounds were screened for their ability to modulate multidrug resistance in various cancer cell lines, demonstrating promising reversal activity against P-glycoprotein, MRP1, and BCRP-mediated drug resistance. The results indicate that these compounds can selectively inhibit transporters, with some showing exceptional efficacy at nanomolar concentrations.
Another significant patent involves the "Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents." This invention presents a novel series of amine-containing flavonoids aimed at treating parasitic infections, particularly Leishmaniasis. The methods outlined in this patent provide a promising avenue for the prevention and treatment of such diseases.
Career Highlights
Iris has worked with esteemed institutions such as The Hong Kong Polytechnic University and McGill University. Her research has not only contributed to academic knowledge but has also paved the way for practical applications in medicine.
Collaborations
Iris has collaborated with notable colleagues, including Larry Ming-Cheung Chow and Kin-Fai Chan. These partnerships have enhanced her research and expanded the impact of her inventions.
Conclusion
Iris Lai King Wong's innovative work in developing compounds for cancer treatment and parasitic infections highlights her significant contributions to medicinal chemistry. Her patents reflect her commitment to addressing critical health challenges through scientific innovation.