Ingunn B Rasmussen

Title: Ingunn B Rasmussen: Innovator in Immunology

Introduction

Ingunn B Rasmussen is a notable inventor based in Oslo, Norway. She has made significant contributions to the field of immunology, particularly through her innovative work on modified immunoglobulin molecules. Her research focuses on enhancing the immune response, which has important implications for cancer treatment and vaccination strategies.

Latest Patents

Ingunn B Rasmussen holds a patent for a modified immunoglobulin molecule that incorporates an antigen in a non-CDR loop region. This invention allows for the incorporation of foreign antigenic peptides, such as a ras peptide, into the immunoglobulin structure. The modified immunoglobulin is designed to recognize dendritic antigen presenting cells (APCs), facilitating the uptake of the foreign antigenic peptide. This process enables the presentation of the peptide on MHC II to naive T-helper cells, which in turn stimulates cytotoxic T-cells through the production of interleukin-2 (IL-2). The potential applications of this modified immunoglobulin include stimulating the immune system in cases of tolerance to mutant proteins, such as in certain cancers, and providing vaccination against viral infections.

Career Highlights

Throughout her career, Ingunn B Rasmussen has demonstrated a commitment to advancing immunological research. Her innovative approaches have garnered attention in the scientific community, and her work continues to influence the development of new therapeutic strategies.

Collaborations

Ingunn has collaborated with esteemed colleagues, including Bjarne Bogen and Inger Sandlie. These partnerships have enriched her research and contributed to the advancement of immunological science.

Conclusion

Ingunn B Rasmussen is a pioneering inventor whose work on modified immunoglobulin molecules has the potential to transform immunotherapy and vaccination approaches. Her contributions to the field of immunology are invaluable and continue to inspire future research.