Ikuo Yamashina

Title: Ikuo Yamashina: Innovator in Medical Science

Introduction

Ikuo Yamashina is a notable inventor based in Kyoto, Japan. He has made significant contributions to the field of medical science, particularly in the development of modified heparins and monoclonal antibodies. With a total of 5 patents, his work has the potential to impact treatments for various medical conditions.

Latest Patents

Yamashina's latest patents include innovations such as low-molecular heparin modification and a remedy for skin ulcers. This invention focuses on modified heparins, specifically low-molecular weight variants that are designed for use in preparing agents for treating skin ulcers. These modified heparins have been substantially deprived of anticoagulant activity while retaining the ability to bind to cell growth factors, cytokines, and cell adhesion molecules. Another significant patent involves a hybridoma and monoclonal antibody MLS102, which recognizes human intestinal cancer cells, particularly their sugar chain of glycoprotein, NeuAc .alpha.2.fwdarw.6GalNAc. This invention also includes a hybridoma that produces the monoclonal antibody, created by fusing splenic cells of a mouse immunized by human intestinal cancer cells with myeloma cells.

Career Highlights

Throughout his career, Ikuo Yamashina has worked on various innovative projects that have advanced medical research. His expertise in modifying heparins and developing monoclonal antibodies showcases his commitment to improving healthcare solutions.

Collaborations

Yamashina has collaborated with notable individuals in his field, including Minoru Okayama and Ken-ichi Toda. These partnerships have likely contributed to the success of his inventions and patents.

Conclusion

Ikuo Yamashina's contributions to medical science through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in treatment options for patients.