Igor V Koptyug

Title: Igor V Koptyug: Innovator in MRI Technology

Introduction

Igor V Koptyug is a prominent inventor based in Novosibirsk, Russia. He has made significant contributions to the field of magnetic resonance imaging (MRI) through his innovative research and patents. His work focuses on the creation of long-lived singlet states of gases, which have potential applications in bio-imaging.

Latest Patents

Igor V Koptyug holds a patent for the "Creation of long-lived singlet states of gases and their use as inhalable MRI contrast agents." This patent utilizes Parahydrogen Induced Polarization to prepare a nuclear singlet state between methylene and methyl protons in propane gas. The low-field MRI technique preserves this singlet state with a remarkable lifetime of T=4.7±0.5 s. The Spin-Lock Induced Crossing (SLIC) method transforms the singlet state into observable nuclear magnetization, suitable for MRI with sub-millimeter and sub-second spatial and temporal resolution, achieving a signal enhancement of over 10,000 times. The long-lived spin states created in hyperpolarized propane gas can be detected directly at 0.0475 T. This non-toxic nature of propane gas could be beneficial for bio-imaging applications, including pulmonary low-field MRI.

Career Highlights

Igor V Koptyug has demonstrated the feasibility of high-resolution low-field 2D gradient-echo MRI with impressive spatial and temporal resolutions of 0.88×0.88 mm and approximately 0.7 s, respectively, at 0.0475 T. His research paves the way for low-cost, high-resolution, high-speed MRI of gases, particularly for imaging the lungs.

Collaborations

Igor collaborates with Kirill V Kovtunov, contributing to advancements in MRI technology and enhancing the potential applications of their research.

Conclusion

Igor V Koptyug's innovative work in MRI technology showcases the potential of using long-lived singlet states of gases for bio-imaging applications. His contributions are paving the way for advancements in medical imaging techniques.