Title: Ian Fraser Pryme: Innovator in Genetic Engineering
Introduction: Ian Fraser Pryme is a notable inventor based in Bergen, Norway. He is associated with Unitargeting Research AS, where he contributes to advancements in genetic engineering. Despite having no granted patents, his work in the field is significant and reflects his innovative spirit.
Latest Patent Applications: Ian Fraser Pryme has submitted several patent applications that showcase his expertise. One of his latest applications is titled "Rational Library." This invention relates to a method for generating rational libraries comprising genetic elements involved in transcriptional and/or translational regulation of a gene. The aim is to increase the production yield of the encoded protein, along with the rational library and its applications. Another application is "Genetically Modified Eukaryotic Cells." This invention describes a method for producing genetically modified eukaryotic cells with optimized growth characteristics. It involves integrating a recombinant first nucleotide sequence into a desired position in the genome, which contains at least one gene encoding a plasma membrane protein with either toxin-receptor or toxic properties. This allows for surface expression-based cell sorting to identify a suitable genomic integration locus. The invention also includes a second exogenous nucleotide sequence containing at least one protein of interest, along with a vector that facilitates the site-specific exchange of the first nucleotide sequence with the second.
Conclusion: Ian Fraser Pryme's contributions to genetic engineering through his innovative patent applications highlight his commitment to advancing the field. His work at Unitargeting Research AS positions him as a key figure in the ongoing development of genetic technologies.