Company Filing History:
Years Active: 2000-2006
Title: The Innovations of Hugh Parker
Introduction
Hugh Parker is an accomplished inventor based in Oakland, CA. He has made significant contributions to the field of biotechnology, particularly in the analysis and separation of platelet-derived growth factor proteins. With a total of 3 patents to his name, Parker's work has had a notable impact on medical research and applications.
Latest Patents
Hugh Parker's latest patents focus on methods for improving the purification and quantification of platelet-derived growth factor (PDGF) proteins that exhibit structural heterogeneity. His innovative techniques utilize TSK sulfopropyl cation exchange chromatography and reverse phase high-performance liquid chromatography to achieve substantially pure isoforms of these proteins. Additionally, he has developed a reverse charged capillary zone electrophoresis method that enables the quantification of these isoforms, which result from endoproteolytic post-translational modifications. The compositions he has invented include substantially purified isoforms of secreted PDGF proteins, specifically intact, single-clipped, and double-clipped isoforms of recombinant PDGF-BB. Furthermore, his patents encompass pharmaceutical compositions that incorporate these purified recombinant PDGF isoforms and methods for their application in promoting wound healing.
Career Highlights
Hugh Parker has built a successful career at Chiron Corporation, where he has been instrumental in advancing biotechnological research. His expertise in protein purification and quantification has positioned him as a key figure in the development of therapeutic applications involving PDGF proteins.
Collaborations
Throughout his career, Parker has collaborated with notable colleagues, including Michael G Kunitani and An D Tran. These partnerships have further enhanced his research and contributed to the success of his innovative projects.
Conclusion
Hugh Parker's contributions to the field of biotechnology through his patents and research have significantly advanced the understanding and application of platelet-derived growth factor proteins. His work continues to influence medical research and therapeutic development, showcasing the importance of innovation in the scientific community.