Company Filing History:
1 out of 832,891 Years Active: 2004
Title: **Howie Tjiong: Innovating Non-Specific Binding Solutions in Electrochemiluminescence**
Introduction
Howie Tjiong, an inventive mind based in Holland, MI, has made a significant impact in the field of electrochemiluminescence with his innovative patent. His pioneering work aims to enhance the performance of assays by reducing non-specific binding, which is crucial for obtaining accurate and reliable results in biological experiments.
Latest Patents
Tjiong holds a patent titled "ECL labels having improved non-specific binding properties, methods of using and kits containing the same." This invention introduces bipyridine or phenanthroline ligands that contain functional groups designed to mitigate non-specific binding. Particularly, these negatively charged functional groups do not interfere with standard amide bond conjugation conditions for biological reagents. The patent also encompasses luminescent metal complexes utilizing these ligands, demonstrating their effectiveness in electrochemiluminescence assays. The findings suggest that Tjiong's labels significantly diminish non-specific binding compared to traditional labels that lack these functional enhancements.
Career Highlights
Throughout his career, Howie Tjiong has focused on advancing the methodologies used in various electrochemiluminescence applications. His dedication to innovation in assay design and implementation has positioned him as a notable figure in the scientific community.
Collaborations
Tjiong has collaborated with esteemed colleagues in his field, including George B Sigal and Liwen Dong. Their collective expertise contributed to the successful development and refinement of Tjiong's patented technology, showcasing the importance of teamwork in scientific innovation.
Conclusion
Howie Tjiong’s contributions to the field of electrochemiluminescence through his innovative patent exemplify how targeted research and inventive thinking can lead to substantial advancements in scientific methods. His work not only enhances the reliability of assays but also sets a precedent for future developments in the industry.