Company Filing History:
Years Active: 1983-1984
Title: The Innovations of Howard E Greene
Introduction
Howard E Greene is a notable inventor based in Carlsbad, CA (US). He has made significant contributions to the field of immunometric assays, holding a total of 2 patents. His work primarily focuses on the use of monoclonal antibodies for the determination of antigenic substances in various fluids.
Latest Patents
Greene's latest patents describe innovative 'two-site' or 'sandwich' immunometric assay techniques. These techniques are designed for the determination of the presence and/or concentration of antigenic substances in fluids using monoclonal antibodies. The patents compare these methods to conventional assays that utilize polyclonal antibodies. Additionally, they detail inhibition assays that employ complexes of antigens with a monoclonal antibody. In these assays, one monoclonal antibody is presented in a soluble labeled form, while a second monoclonal antibody is bound to a solid carrier. The soluble and bound monoclonal antibodies may originate from either the same or different cell lines, with each monoclonal antibody exhibiting an affinity for the antigenic substances of at least about 10^8 liters/mole.
Career Highlights
Howard E Greene is associated with Hybritech Incorporated, a company known for its advancements in biotechnology. His work at Hybritech has allowed him to contribute to the development of innovative diagnostic tools that have the potential to improve medical testing and patient outcomes.
Collaborations
Greene has collaborated with Gary S David, who is also involved in the field of immunometric assays. Their partnership has likely fostered advancements in the techniques and applications of monoclonal antibodies.
Conclusion
Howard E Greene's contributions to immunometric assays and his innovative use of monoclonal antibodies have positioned him as a significant figure in the field of biotechnology. His patents reflect a commitment to advancing medical diagnostics and improving the accuracy of antigen detection.