Company Filing History:
Years Active: 1995-1996
Title: Hiroshi Kawaide: Innovator in Microbial Biotechnology
Introduction
Hiroshi Kawaide is a notable inventor based in Fujimi, Japan. He has made significant contributions to the field of microbial biotechnology, particularly in the conversion of bile acids using Bacillus strains. With a total of 2 patents, Kawaide's work has implications for both medical and industrial applications.
Latest Patents
Kawaide's latest patents focus on the use of microorganisms from the genus Bacillus to oxidize hydroxy groups of cholic acid and chenodeoxycholic acid. One of his patents describes a process where Bacillus strains convert chenodeoxycholic acid to 3-alpha-hydroxy-7-keto-5-beta-cholanic acid under aerobic conditions and alkaline pH. The preferred strains for this process include Bacillus FERM BP-4390, Bacillus FERM BP-4391, Bacillus FERM BP-3651, Bacillus FERM BP-3393, Bacillus FERM BP-3398, Bacillus FERM BP-3395, and Bacillus FERM BP-3396. Another patent details the conversion of cholic acid to 3-alpha-hydroxy-7,12-diketo-5-beta-cholanic acid, also under aerobic conditions and alkaline pH, using Bacillus FERM BP-3393 and Bacillus FERM BP-3398. Additionally, Kawaide has developed a process for preparing 3.alpha., - 3-.alpha., 7-.alpha.-dihydroxy-12-keto-5-.beta.-cholanic acid from cholic acid through alkalophilic Bacillus strains, specifically Bacillus sp. FERM BP-3394 and Bacillus sp. FERM BP-3397.
Career Highlights
Hiroshi Kawaide is currently associated with Tokyo Tanabe Company, Ltd., where he continues to innovate in the field of biotechnology. His research has not only advanced scientific understanding but also opened new avenues for practical applications in medicine and industry.
Collaborations
Kawaide has worked alongside notable colleagues such as Hiromi Kimura and Akio Okamura. Their collaborative efforts have contributed to the success of various projects and patents in the field.
Conclusion
Hiroshi Kawa