Company Filing History:
7 out of 396 
4 out of 789 
1 out of 820 
Years Active: 2008-2017
Title: Innovator Hiroshi Aiba – Pioneering Glucose Dehydrogenase
Introduction
Hiroshi Aiba, an accomplished inventor based in Tsuruga, Japan, holds a remarkable portfolio of 11 patents. His innovative contributions, particularly in the field of glucose dehydrogenase, have significantly impacted the domain of self-monitoring blood glucose (SMBG) devices.
Latest Patents
One of Aiba's notable inventions is a novel glucose dehydrogenase that offers exceptional substrate specificity. This patented enzyme is characterized by several key features. Firstly, it remains stable at temperatures of 45°C or lower. Secondly, it operates effectively within a pH range of 4.5 to 7.5. Thirdly, the reactivity to D-xylose, maltose, or D-galactose is minimal (2% or less) compared to its reactivity to D-glucose, which is set as the standard. Additionally, this glucose dehydrogenase demonstrates optimal activity temperatures ranging from 34 to 47°C, with an ideal pH for its activity between 6.3 and 6.7. Another invention includes a flavin adenine dinucleotide-dependent glucose dehydrogenase comprising a polypeptide with over 78% sequence identity to a specified amino acid sequence, maintaining the essential glucose dehydrogenase activity.
Career Highlights
Throughout his career, Hiroshi Aiba has been associated with prominent companies including Toyobo Co., Ltd. and Toyo Boseki Kabushiki Kaisha. His work has not only contributed to the advancement of glucose monitoring technologies but has also established him as a respected name in the research community.
Collaborations
Aiba has collaborated with notable professionals in his field, including Takahide Kishimoto and Yosuke Sumida. These partnerships have enhanced the development of his innovations and have fostered significant advancements in glucose dehydrogenase research.
Conclusion
Hiroshi Aiba continues to innovate and push the boundaries of scientific research with his inventions, particularly in glucose dehydrogenase. His work exemplifies the profound impact of inventors on healthcare technology, ultimately aiming to improve the quality of life for those managing diabetes.