Location History:
- Kamakura, JA (1977)
- Kamakura, JP (1997)
Company Filing History:
Years Active: 1977-1997
Title: Hirohiko Shimizu: Innovator in Serine Protease and Hydrogel Technologies
Introduction
Hirohiko Shimizu is a prominent inventor based in Kamakura, Japan. He has made significant contributions to the fields of biochemistry and materials science, particularly through his innovative patents. With a total of 2 patents, Shimizu's work focuses on advancements that have potential applications in medical treatments and drug delivery systems.
Latest Patents
Shimizu's latest patents include groundbreaking inventions related to serine protease and hydrogel technologies. The first patent, titled "Serine protease and serine protease gene," presents a serine protease exhibiting biological activity, characterized by a specific polypeptide sequence. This invention also details a serine protease precursor that includes a cleavable peptide or signal peptide at its N-terminal. The gene encoding these components is crucial for producing the serine protease in large quantities, which can be beneficial in medical treatment fields. Additionally, the invention provides a DNA sequence coding for a transcription controlling region necessary for gene expression specific to human leukocytes or erythrocytes.
The second patent, "Hydrogel and production thereof," describes a novel and stable hydrogel that incorporates a water-soluble polymer with a chelating agent bound to its polymer chain. This hydrogel utilizes polyvalent metal ions to cross-link polymer molecules through the chelating agent. It serves as a carrier for the timed release of drugs and medicaments, showcasing its potential in therapeutic applications.
Career Highlights
Hirohiko Shimizu is associated with Toray Industries, Inc., a leading company in advanced materials and chemicals. His work at Toray has allowed him to explore innovative solutions that bridge the gap between scientific research and practical applications in various industries.
Collaborations
Shimizu has collaborated with notable colleagues, including Hitoshi Ozawa and Yosuke Aoki. These collaborations have contributed to the development of his patents and the advancement of research in his field.
Conclusion
Hirohiko Shimizu's contributions to serine protease and hydrogel technologies highlight his role as an influential inventor. His innovative patents not only advance scientific knowledge but also hold promise for practical applications in medicine and drug delivery.