Company Filing History:
9 out of 55 
3 out of 67 
Years Active: 1997-2006
Title: Henry W Founds: Innovator in Monoclonal Antibody Research
Introduction
Henry W Founds is a notable inventor based in Mendham, NJ (US), recognized for his contributions to the field of biomedical research. He holds a total of 10 patents, showcasing his innovative spirit and dedication to advancing medical science.
Latest Patents
One of his significant inventions is a monoclonal antibody specific for advanced glycosylation endproducts (AGEs) in biological samples. This invention relates to monoclonal antibodies that target AGEs formed in vivo and are cross-reactive with those formed in vitro. The monoclonal antibody, or an antigen-binding fragment thereof, demonstrates immunological binding characteristics similar to monoclonal antibody 4G9, which was produced by hybridoma 4G9 and deposited with the American Type Culture Collection (ATCC) under Accession Number CRL 11626 on April 27, 1994. The 4G9 antibody is utilized in a sandwich ELISA to detect various AGEs, including ApoB-AGE, IgG-AGE, collagen-AGE, serum-AGE peptides, and urinary-AGE peptides and proteins. Furthermore, Founds has developed methods for measuring and lowering the accumulation of AGEs, particularly in individuals who smoke or use tobacco, highlighting the increased levels of AGEs in these populations.
Career Highlights
Throughout his career, Henry W Founds has worked with prominent organizations, including Alteon Incorporated and The Picower Institute for Medical Research. His work has significantly impacted the understanding and treatment of diseases related to advanced glycosylation endproducts.
Collaborations
Founds has collaborated with esteemed colleagues such as Homayoun Sadeghi and Richard J Bucala, contributing to the advancement of research in his field.
Conclusion
Henry W Founds is a distinguished inventor whose work in monoclonal antibody research has paved the way for innovative diagnostic and therapeutic methods. His contributions continue to influence the biomedical field and improve health outcomes.