Henning Ralf Stennicke

Title: The Innovations of Henning Ralf Stennicke

Introduction

Henning Ralf Stennicke is a notable inventor based in Frederiksberg, Denmark. He has made significant contributions to the field of biochemistry, particularly in the development of customized proteases. With a total of 2 patents to his name, Stennicke's work has implications for various applications in enzymology and biotechnology.

Latest Patents

Stennicke's latest patents focus on customized proteases, which are mutant enzymes designed to enhance specific biochemical reactions. These inventions provide methods for creating customized proteases derived from known proteases. The altered transacylation reactions enable the performance of reactions that are not substantially catalyzed by the original protease, or they improve yields in existing reactions. The methods involve site-specific or random mutagenesis of the active site amino acids of known proteases. Additionally, the customized proteases can be used to prepare preselected transacylation products, which can be modified by substituting nucleophiles such as L-amino acids, D-amino acids, amino acid amides, and radioactive amino acids.

Career Highlights

Henning Ralf Stennicke is currently associated with Carlsberg A/S, where he continues to innovate in the field of protease research. His work has contributed to advancements in enzyme technology, which are crucial for various industrial applications.

Collaborations

Stennicke has collaborated with notable colleagues such as Klaus Breddam and Morten C Kielland-Brandt. These collaborations have further enriched his research and development efforts in the field of customized proteases.

Conclusion

Henning Ralf Stennicke's contributions to the field of biochemistry through his innovative work on customized proteases highlight the importance of enzyme technology in modern science. His patents and collaborations reflect a commitment to advancing the understanding and application of proteases in various industries.