Cambridge, United Kingdom

Hendricus Renerus Jacobus Mattheus Hoogenboom

USPTO Granted Patents = 7 


Average Co-Inventor Count = 6.5

ph-index = 6

Forward Citations = 1,045(Granted Patents)


Company Filing History:


Years Active: 2003-2007

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7 patents (USPTO):Explore Patents

Title: Hendricus Renerus Jacobus Mattheus Hoogenboom: Innovator in Antibody Production

Introduction

Hendricus Renerus Jacobus Mattheus Hoogenboom is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of antibody production, holding a total of 7 patents. His work focuses on innovative methods for producing anti-self antibodies, which have important implications in medical research and therapeutic applications.

Latest Patents

Hoogenboom's latest patents include groundbreaking methods for the production of anti-self antibodies from antibody segment repertoires displayed on phage. These methods involve creating a library of replicable genetic display packages (rgdps) that showcase specific binding pairs, which are antibodies or antibody fragments. The rgdps contain nucleic acid sequences derived from a particular species of mammal, allowing for the selection of antibody fragments that bind to self antigens. This innovative approach enables the production of various antibody fragments, such as scFv, Fd, and Fab, which are essential for binding antigens effectively.

Career Highlights

Throughout his career, Hoogenboom has worked with esteemed organizations, including the Medical Research Council. His research has significantly advanced the understanding of antibody production and its applications in immunology. His innovative methods have paved the way for new therapeutic strategies in treating autoimmune diseases and other related conditions.

Collaborations

Hoogenboom has collaborated with notable colleagues, including Andrew David Griffiths and James David Marks. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in the field of antibody research.

Conclusion

Hendricus Renerus Jacobus Mattheus Hoogenboom is a distinguished inventor whose work in antibody production has made a lasting impact on medical research. His innovative methods and collaborations continue to drive advancements in the field, showcasing the importance of creativity and collaboration in scientific discovery.

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