Company Filing History:
Years Active: 1999
Title: Innovator Spotlight: Han-Ting Chang
Introduction
Han-Ting Chang is a noted inventor based in San Diego, California. He has made significant contributions to the field of chemistry, particularly through his innovative patent that focuses on asymmetric aminohydroxylation of olefins. This groundbreaking work demonstrates the potential of catalyzed addition reactions in synthesizing valuable chemical compounds.
Latest Patents
Han-Ting Chang is credited with one patent titled "Catalytic Asymmetric Aminohydroxylation of Olefins with Sulfonamides." This patent outlines a method for synthesizing β-hydroxyamines and β-hydroxysulfonamides from olefin substrates using a catalyzed asymmetric addition reaction. The process involves the use of osmium as a catalyst, alongside chiral ligands, which enhance the regio- and enantioselectivity of the reaction. Notably, divalent ligands are preferred, achieving excellent yields and enantiomeric efficiencies when co-solvents containing a 50/50 mixture of water and an organic solvent are employed. Furthermore, β-hydroxyamines are obtained by deprotecting the corresponding β-hydroxysulfonamides.
Career Highlights
Currently associated with The Scripps Research Institute, Han-Ting Chang has established himself as an influential figure in the academic and industrial chemistry landscape. His work exhibits a profound understanding of complex chemical reactions and highlights his commitment to advancing the field through innovative research.
Collaborations
Throughout his career, Han-Ting Chang has collaborated with esteemed scientists such as K Barry Sharpless and Guigen Li. These partnerships have enabled him to refine his research approaches and contribute effectively to the scientific community, paving the way for future advancements in chemical synthesis.
Conclusion
In summary, Han-Ting Chang stands out as a prominent inventor in the realm of asymmetric aminohydroxylation. His patent not only showcases his innovative capabilities but also underscores the significance of collaboration in the field of chemistry. The contributions he has made through his research at The Scripps Research Institute continue to inspire upcoming generations of chemists and inventors alike.