Company Filing History:
Years Active: 2022
Title: Gregory Goldberg: Innovator in CRISPR-Cas DNA Editing
Introduction
Gregory Goldberg is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of genetic engineering, particularly through his work on CRISPR technology. His innovative approach has led to advancements in DNA editing methods that hold great promise for various applications in biotechnology.
Latest Patents
Goldberg holds a patent for "Compositions and methods for transcription-based CRISPR-Cas DNA editing." This patent provides compositions and methods for cleaving a DNA sequence in a cell. The methods involve introducing a recombinant vector containing a clustered regularly interspaced short palindromic repeats (CRISPR) system into a cell. The system includes a CRISPR RNA (crRNA) targeted to a specific DNA sequence that is operatively linked to a promoter, along with CRISPR-associated enzymes (Cas) 10, Cas6, and at least one Csm protein. The Cas 10 enzyme cleaves the DNA sequence only during the transcription of the DNA sequence linked to the promoter. Additionally, the patent includes recombinant vectors for modifying cells, cells that contain these vectors, and kits that feature the modified vectors.
Career Highlights
Goldberg's career is marked by his dedication to advancing genetic research and technology. He is affiliated with The Rockefeller University, where he collaborates with leading scientists in the field. His work has not only contributed to academic knowledge but also has potential implications for therapeutic applications.
Collaborations
Goldberg has worked alongside notable colleagues such as Luciano Marraffini and Poulami Samai. Their collaborative efforts have further enhanced the research and development of CRISPR technologies.
Conclusion
Gregory Goldberg's innovative contributions to CRISPR-Cas DNA editing exemplify the potential of genetic engineering to transform biotechnology. His work continues to inspire advancements in the field and holds promise for future applications.