Gregory Duke

Title: Gregory Duke: Innovator in Influenza Virus Production

Introduction

Gregory Duke is a prominent inventor based in Redwood City, CA, known for his significant contributions to the field of virology. With a total of 12 patents to his name, Duke has focused on developing innovative methods and systems for the production of influenza viruses, particularly for use in vaccines.

Latest Patents

Duke's latest patents include a multi-plasmid system for the production of influenza viruses. This invention provides vectors and methods suitable for creating recombinant influenza vaccines in cell culture. The system enhances the ability of influenza viruses to replicate in embryonated chicken eggs and various cell types, such as Vero and MDCK cells. Additionally, his work includes an improved method of rescue, where animal cells are electroporated with the plasmids and vectors he developed. Another notable patent involves methods and compositions for expressing negative-sense viral RNA in canine cells, utilizing novel canine pol I regulatory nucleic acid sequences.

Career Highlights

Throughout his career, Gregory Duke has worked with notable companies in the biotechnology sector, including MedImmune Limited and MedImmune Vaccines, Inc. His work has significantly advanced the understanding and production of influenza viruses, contributing to public health initiatives.

Collaborations

Duke has collaborated with esteemed colleagues in his field, including George William Kemble and Richard R. Spaete. These collaborations have further enriched his research and innovations in virology.

Conclusion

Gregory Duke's innovative work in the production of influenza viruses has made a lasting impact on vaccine development. His contributions continue to play a crucial role in enhancing public health through improved vaccine technologies.