Calabasas, CA, United States of America

Gregory A Horwitz


Average Co-Inventor Count = 3.0

ph-index = 2

Forward Citations = 5(Granted Patents)


Company Filing History:


Years Active: 2004-2005

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4 patents (USPTO):Explore Patents

Title: Innovations by Gregory A. Horwitz

Introduction

Gregory A. Horwitz is a notable inventor based in Calabasas, California. He has made significant contributions to the field of biomedical research, particularly in the development of innovative therapies targeting pituitary tumor transforming gene (PTTG) proteins. With a total of four patents to his name, his work has the potential to impact cancer treatment and research.

Latest Patents

Horwitz's latest patents include isolated antibodies that specifically bind to murine pituitary tumor transforming gene carboxy-terminal (PTTG-C) peptides. These antibodies are useful in assays to determine levels of PTTG proteins or PTTG-C peptides in various samples, including tissue samples and biological fluids. Additionally, they can purify PTTG proteins from crude cell extracts. His work also encompasses methods to inhibit neoplastic cellular proliferation and transformation using PTTG-C peptides, which can regulate PTTG expression in a dominant negative manner. Furthermore, he has developed compositions aimed at inhibiting tumor angiogenesis and neoplastic cellular proliferation, including kits for in vitro or in vivo treatment.

Career Highlights

Horwitz is affiliated with Cedars-Sinai Medical Center, where he continues to advance his research and innovations. His work is characterized by a strong focus on therapeutic applications of his inventions, particularly in the context of cancer biology.

Collaborations

He has collaborated with notable colleagues, including Xun Zhang and Shlomo Melmed, to further enhance the impact of his research and innovations.

Conclusion

Gregory A. Horwitz's contributions to the field of biomedical research through his patents and collaborations highlight his commitment to advancing cancer treatment. His innovative approaches to targeting PTTG proteins may pave the way for new therapeutic strategies in oncology.

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