Gowthami M Arepally

Title: Gowthami M Arepally: Innovator in Medical Diagnostics

Introduction

Gowthami M Arepally is a notable inventor based in Durham, NC (US). He has made significant contributions to the field of medical diagnostics, particularly in the area of heparin induced thrombocytopenia and thrombosis. With a total of 2 patents, his work has the potential to impact patient care and treatment options.

Latest Patents

Gowthami M Arepally's latest patents focus on compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis. The invention includes compositions, kits, and methods comprising a monoclonal antibody that shares key functional properties with polyclonal antibodies involved in the pathogenesis of heparin induced thrombocytopenia/thrombosis (HIT/HITT) in mammals. This monoclonal antibody preferentially binds with a PF4/heparin complex, enhancing its effectiveness compared to binding with PF4 or heparin alone. Additionally, it binds specifically with PF4 in a complex with other glycosaminoglycans besides heparin and activates platelets. The invention also includes a humanized version of the monoclonal antibody and a process for humanizing it.

Career Highlights

Throughout his career, Gowthami M Arepally has worked with reputable organizations such as Science & Technology Corporation and Stc.unm. His experience in these companies has contributed to his expertise in the field of medical research and innovation.

Collaborations

Gowthami has collaborated with notable individuals in his field, including Walter Kisiel and Keiko Kamei. These collaborations have likely enriched his research and development efforts.

Conclusion

Gowthami M Arepally is a distinguished inventor whose work in medical diagnostics is paving the way for advancements in the treatment of heparin induced thrombocytopenia/thrombosis. His contributions are significant and hold promise for improving patient outcomes.