Gillian Clarke

Title: Gillian Clarke: Innovator in Liquid Formulations

Introduction

Gillian Clarke is a notable inventor based in Middlesex, GB. She has made significant contributions to the field of pharmaceutical formulations, particularly in the development of liquid formulations for compounds that act at sulfonylurea receptors. Her work is essential for improving the delivery of medications used in treating diabetes.

Latest Patents

Gillian Clarke holds a patent for "Liquid formulations of compounds active at sulfonylurea receptors." This invention provides liquid formulations that are suitable for intravenous and intra-arterial infusion. The formulations include compounds such as glibenclamide, tolbutamide, and repaglinide, among others. These liquid formulations can be concentrated solutions for storage or diluted for bolus injections and extended infusions. For instance, a formulation may contain at least about 0.05 mg/ml glibenclamide in a water-based solution with 40% polyethylene glycol 300, 10% ethanol, and 50% water, maintaining a pH of about 9. This solution is designed to be stable for storage and can be diluted without precipitation.

Career Highlights

Gillian Clarke is currently associated with Biogen Chesapeake LLC, where she continues to innovate in the field of pharmaceutical formulations. Her expertise in creating effective liquid formulations has positioned her as a valuable asset in her company.

Collaborations

Gillian has collaborated with notable colleagues such as Sven Jacobson and Rajinder Matharu. Their combined efforts contribute to advancing research and development in the pharmaceutical industry.

Conclusion

Gillian Clarke's work in liquid formulations for sulfonylurea receptor compounds showcases her innovative spirit and dedication to improving medical treatments. Her contributions are vital for enhancing the efficacy of diabetes medications and advancing pharmaceutical science.