Company Filing History:
Years Active: 2002-2004
Title: Gildas Le Gal La Salle: Innovator in Gene Therapy
Introduction
Gildas Le Gal La Salle is a prominent inventor based in Saint Cloud, France. He has made significant contributions to the field of gene therapy, particularly through his work with adenovirus vectors. With a total of 2 patents, his innovations are paving the way for advancements in the treatment of diseases affecting the central nervous system.
Latest Patents
One of his latest patents involves adenovirus vectors designed for the transfer of foreign genes into cells of the central nervous system, particularly the brain. This invention focuses on a recombinant DNA vector that can direct the expression and/or transcription of a selected nucleotide sequence in these cells. The vector comprises at least part of the genome of an adenovirus, which includes the necessary regions for the virus to penetrate cells that are normally infectable by it. This recombinant vector is particularly useful in treating diseases of the central nervous system and in gene therapy.
Another significant patent by Gildas Le Gal La Salle is related to assays for promoter operability in central nervous system cells. Similar to his previous invention, this recombinant DNA vector is capable of directing the expression and/or transcription of a selected nucleotide sequence in the cells of the central nervous system. It also includes part of the adenovirus genome and is designed to be inserted under the control of a promoter that is operative in these cells. This innovation further enhances the potential for gene therapy applications.
Career Highlights
Gildas Le Gal La Salle is currently associated with Aventis Pharma S.A., where he continues to contribute to groundbreaking research in gene therapy. His work has been instrumental in advancing the understanding and treatment of various neurological diseases.
Collaborations
Throughout his career, Gildas has collaborated with notable figures in the field, including Axel Kahn and Jacques Mallet. These collaborations have enriched his research and expanded the impact of his inventions.
Conclusion
Gildas Le Gal La Salle is a key figure in the realm of gene therapy, with innovative patents that hold promise for treating central nervous system diseases. His contributions continue to influence the future of medical science and therapy.