Company Filing History:
Years Active: 2001-2004
Title: Gerald M. Fleischner: Innovator in Treating Irritable Bowel Syndrome
Introduction
Gerald M. Fleischner is a notable inventor based in Chappaqua, NY (US). He has made significant contributions to the field of medicine, particularly in the treatment of irritable bowel syndrome (IBS). With a total of 3 patents, his work focuses on innovative methods and compositions that enhance patient care.
Latest Patents
One of his latest patents is a method and composition for treating irritable bowel syndrome using low doses of opioid receptor antagonists. This invention relates to a method for treating a subject with IBS, which comprises long-term administration of an opioid receptor antagonist at an appropriately low dose. This approach selectively antagonizes excitatory opioid receptor functions while preserving inhibitory functions in myenteric neurons in the intestinal tract and neurons of the central nervous system (CNS). The administration of the opioid receptor antagonist at a low dose enhances the potency of the inhibitory effects of endogenous opioid peptides present in the intestinal tract and the CNS. This innovation aims to reduce abdominal pain and stool frequency resulting from abnormally supersensitized excitatory opioid receptor functions. The invention also includes a composition for treating a subject with IBS, which comprises an effective dose of an opioid receptor antagonist and a pharmaceutically acceptable carrier.
Career Highlights
Gerald M. Fleischner is affiliated with the Albert Einstein College of Medicine, where he continues to advance his research and innovations in the medical field. His work has garnered attention for its potential to improve the quality of life for individuals suffering from IBS.
Collaborations
Some of his notable coworkers include Stanley M. Crain and Ke-fei Shen, who have contributed to his research endeavors.
Conclusion
Gerald M. Fleischner's innovative approaches to treating irritable bowel syndrome highlight his commitment to improving patient outcomes through scientific research and collaboration. His contributions to the field are invaluable and continue to pave the way for future advancements in medical treatments.