Gerald Cohen

Title: Gerald Cohen: Innovator in Antibody and Antimicrobial Research

Introduction

Gerald Cohen is a notable inventor based in Raanana, Israel. He has made significant contributions to the fields of antibody research and antimicrobial agents. With a total of 6 patents to his name, Cohen's work has had a substantial impact on medical science.

Latest Patents

Cohen's latest patents include a single chain antibody against mutant p53. This invention addresses the common mutations found in the p53 protein, which often lead to a conformational change that exposes a hidden epitope. The single chain antibody (scFv) specifically recognizes this mutant epitope in p53, while leaving the wild type p53 unaffected. Additionally, he has developed pharmaceutical compositions that utilize this antibody and methods for treatment using these compositions. Another significant patent involves recombinant Staphylococcus thioredoxin reductase and its inhibitors, which are useful as antimicrobial agents. This patent provides isolated and purified Staphylococcus thioredoxin reductases (TrxB), along with polynucleotides encoding the TrxBs, vectors, and host cells. It also includes methods for isolating and producing recombinant TrxBs, as well as techniques for screening compounds that modulate TrxB activity.

Career Highlights

Throughout his career, Cohen has worked with prestigious institutions, including Tel Aviv University and Gist-Brocades N.V. His research has been pivotal in advancing the understanding of antibodies and their applications in medicine.

Collaborations

Cohen has collaborated with notable colleagues such as Yair Aharonowitz and Rachel Schreiber. Their joint efforts have contributed to the success of his research and innovations.

Conclusion

Gerald Cohen's work in antibody and antimicrobial research exemplifies the spirit of innovation in the scientific community. His patents and collaborations continue to influence the field and pave the way for future advancements.