Company Filing History:
Years Active: 1998
Title: George Panayotou: Innovator in Serine Kinase Activity Modulation
Introduction
George Panayotou is a distinguished inventor based in London, GB. He has made significant contributions to the field of biochemistry, particularly in the modulation of PI3-kinase activity. His innovative work has implications for understanding cellular responses to external stimuli.
Latest Patents
George Panayotou holds a patent for "Methods to inhibit serine kinase activity and to alter intersubunit." This invention provides a method to inhibit the binding between the p85 and p110 subunits of PI3-kinase. By targeting specific residues in the inter-SH2 domain of the p85 subunit, his method modulates PI3-kinase activity. This modulation can affect how cells respond to various external stimuli. The invention also includes methods to alter serine kinase activity by disabling the DRHNSN sequence of the p110 subunit, which can lead to changes in overall PI3-kinase activity.
Career Highlights
George Panayotou is associated with the Ludwig Institute for Cancer Research Limited, where he continues to advance research in cancer biology. His work is pivotal in understanding the mechanisms of kinase activity and its implications for cancer treatment.
Collaborations
He has collaborated with notable colleagues, including Ritu Bala Dhand and Michael Derek Waterfield, contributing to a rich environment of innovation and research.
Conclusion
George Panayotou's contributions to the field of biochemistry, particularly through his patent on serine kinase activity modulation, highlight his role as an influential inventor. His work continues to impact cancer research and therapeutic strategies.